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Anaphylaxis – a severe, potentially life-threatening allergic reaction – is usually tied to peanuts or shellfish, but a recent case has brought up a new concern.
According to a report by the American College of Allergy, Asthma and Immunology (ACAAI), a teen experienced a severe allergic reaction from an energy drink.
The case, which was presented at the ACAAI’s 2026 Annual Scientific Meeting held Nov. 12–16 in Phoenix, Arizona, involved a 15-year-old boy who developed "widespread hives," wheezing and difficulty breathing after trying a new beverage.
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The teen was reportedly taken to the hospital, where he received two doses of epinephrine, albuterol — a medication commonly used in rescue inhalers to help open the airways — an antihistamine and IV fluids. His symptoms resolved after treatment.
A review of the drink’s label revealed that it contained 5 grams of collagen derived from cod.
According to the report, the teen reported mild throat itching and lip swelling when eating canned tuna, although he had eaten salmon without an issue. He also has eczema, asthma and allergic rhinitis (commonly called hay fever).
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Despite the teen's symptoms, a skin prick testing for tuna, cod and flounder allergy all returned negative.
These findings represent initial research presented at the ACAAI conference, and have not yet been published in a peer-reviewed journal.
Allergist Annabelle Rowland, M.D., study author and ACAAI member based in Georgia, commented in a news release that this case shows "how tricky fish allergy can be."
"Collagen from fish is showing up in a growing number of products, from drinks to supplements," she said. "Standard fish allergy tests mostly look for a different fish protein and contain very little collagen, so a person can test negative and still react."
In a statement sent to Fox News Digital, a spokesperson for the Council for Responsible Nutrition in Washington, D.C., said that collagen ingredients can come from several animal sources, like fish, cattle and pigs.
"While collagen has been studied for potential benefits related to skin and joint health, consumers should consider their individual health needs and sensitivities when choosing products," they advised.
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"Fish-derived collagen can pose an allergy risk for people sensitive to fish, and processing or hydrolysis does not necessarily eliminate that risk."
The spokesperson recommended those with fish allergies should carefully review product labels, which are required to identify major food allergens, such as fish. Consumers should also consult with their healthcare provider before considering these products.
"The case presented at ACAAI highlights the importance of allergen awareness, but a single suspected reaction does not establish how frequently such reactions occur," they added.
"Product manufacturers are required by law to provide accurate ingredient information and major allergen disclosures so consumers can make informed choices."
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Sung Poblete, Ph.D., CEO of Virginia-based Food Allergy Research & Education, told Fox News Digital that fish collagen is increasingly being used in products like supplements, beverages and wellness items.
"While many people with fish allergy avoid all finned fish, reactions can vary between individuals and between different fish-derived proteins," she said. "So someone can be allergic to one type of fin fish and not another."
Poblete added that labels must identify the species of fish. Crustacean shellfish, such as shrimp, crab and lobster, must also be specifically identified, according to the FDA.
"For someone managing fish or shellfish allergy, 'marine collagen' on a label calls for a closer look at the ingredient list and 'contains' statement," she said. "If the source still isn’t clear, FARE encourages people to call the manufacturer before using the product."
Consumers are encouraged to ask the manufacturer what the collagen is made from, and how the product is sourced, packaged and tested for allergens.
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"This case offers a timely reminder to read every label, including on drinks and supplements, and talk with an allergist about any reaction, even if a test came back negative," Poblete added.
Fox News Digital reached out to energy drink manufacturers for comment.

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